Newcastle Brain Tissue Resource

 

Newcastle Brain Tissue Resource

Welcome to the Newcastle Brain Tissue Resource  
 
Here you can find information about the NBTR and links to various related areas including information for those interested in becoming potential donors. Members of the research community can request tissue using the on-line form or by downloading a form to email to us. If you wish to  apply online you will need to ask to  become an authorised user. 

Downloadable documents for potential donors

If you are interested in donation we would prefer to go through the details with you before you complete the consent form but examples are given below for your reference. Please contact us on nbtr@ncl.ac.uk for further information.

What to do leaflet

Consent on participants behalf
Information for Nominated Representatives
Consent by Participant

Brain Donation leaflet




Downloadable documents for researchers

Tissue application form
Information for applicants
Example Material Transfer Agreement
Access Policy

Downloadable documents for other professionals

NBTR Information for Funeral Directors v2.pdf

NBTR Information for GPs

General information   
 
Newcastle Brain Tissue Resource (formerly Newcastle Brain Bank) was established over 30 years ago and has supported major advances in the understanding of dementia and neurodegenerative disease and identifying therapeutic targets. Current cholinergic therapy for dementia was based in part on studies carried out on tissue from NBTR. It currently receives funding from the MRC and the NIHR funded Biomedical Centre on Ageing. NBTR works in co-operation with other brain banks in the UK and is part of the Brains for Dementia Research network funded by the Alzheimer’s Society and the Alzheimer Research UK. NBTR is licensed by the Human Tissue Authority as a research tissue bank. All tissue is collected with informed consent.
The Application Process
Normally access is granted to those scientists who can show a direct requirement for tissue for research purposes. Scientific research projects should ideally have  independent peer review, although the NBTR recognises that sometimes this is not always possible, such as for small pilot projects which aim to obtain proof of principle data for gaining future funding. Ethical approval is generally requested, although the NBTR can extend ethical approval to  projects within the UK as part of its remit as an HTA and Local Research Ethics Committee approved Tissue Bank. Evidence of  funding 
sufficient to complete the study is required to ensure that applicants have the resources necessary to complete the study. Where possible the NBTR  does recover some of the costs associated with preparing tissue samples.  Cost recovery is now standardised across the UK brain banks and details can be found in the attached document above entitled 'Information for Applicants' .  The NBTR also requests that it is acknowledged, along with its funders, in any publication that arises from work involving NBTR tissue.
Applications for tissue are reviewed by a Committee with an independent Chair and lay representation. This ensures widespread and appropriate use of the tissue.  The Committee will provide comments and feedback on applications.  Normally a decision can be made within 2-3 weeks of receipt of an application although under some circumstances this may take a little longer. Tissue can be sent to  applicants once all  approvals have been obtained and tissue is prepared. This can take several weeks depending on the size and complexity of the tissue request.  A Material Transfer Agreement will be drawn up between Newcastle University and the recipient's institution. Local researchers will be asked to  sign a Local User Agreement.
Downloadable application forms can be accessed above.  If you have any questions please contact the NBTR Manager, Debbie Lett
( d.j.lett@ncl.ac.uk  ) 

      

 

                                                                                                                                                                                                              

News

NBTR on the Radio again!
Chris Morris interviewed on Friday 17th February by Radio Newcastle's Kirsten O'Brien as part of a report on brain donation for research following a US brain banks announcement that there is a shortage of donated brains. The interview can be listened to again on BBC Iplayer radio (approx 90 minutes in).