Newcastle Brain Tissue Resource


Newcastle Brain Tissue Resource

Welcome to the Newcastle Brain Tissue Resource  
Here you can find information about NBTR and links to  related areas including information for those interested in becoming potential donors.  Researchers can request tissue by contacting us for an application form.

Contact Details:  

Newcastle Brain Tissue Resource, Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL

     0191 208 1231 (24 hour donation line 0191 208 1345)

Information for Donors

Newcastle Brain Tissue Resource video

Downloadable documents for researchers
NB The tissue application form is available here as a pdf for reference.  A word version with more functionality is available from the NBTR Manager for electronic use. 

Brain Map Part 1

NBTR Tissue application form v 2 
Tissue request Information Sheet
Example Material Transfer Agreement
Access Policy

Downloadable documents for other professionals

NBTR Information for Funeral Directors v2.pdf

NBTR Information for GPs

General information   
Newcastle Brain Tissue Resource (formerly Newcastle Brain Bank) was established over 30 years ago and has supported major advances in the understanding of dementia and neurodegenerative disease and identifying therapeutic targets. Current cholinergic therapy for dementia was based in part on studies carried out on tissue from NBTR. It currently receives funding from the MRC and the NIHR funded Biomedical Centre on Ageing. NBTR works in co-operation with other brain banks in the UK and is part of the Brains for Dementia Research network funded by the Alzheimer’s Society and the Alzheimer Research UK. NBTR operates under a Human Tissue Authority licence and has full ethical approval as a research tissue bank. All tissue is collected with informed consent.
The Application Process
Normally access is granted to those scientists who can show a direct requirement for tissue for research purposes. Scientific research projects should ideally have  independent peer review, although the NBTR recognises that sometimes this is not always possible, such as for small pilot projects which aim to obtain proof of principle data for gaining future funding. Ethical approval is generally requested, although the NBTR can extend ethical approval to  projects within the UK as part of its remit as an HTA and Local Research Ethics Committee approved Tissue Bank. Evidence of  funding 
sufficient to complete the study is required to ensure that applicants have the resources necessary to complete the study. Wherever possible the NBTR  does recover some of the costs associated with preparing tissue samples.  Cost recovery is now standardised across the UK brain banks and details can be found at  The NBTR also requests that it is acknowledged, along with its funders, in any publication that arises from work involving NBTR tissue.
Applications for tissue are reviewed by a Committee with an independent Chair and lay representation. This ensures widespread and appropriate use of the tissue.  The Committee will provide comments and feedback on applications.  Normally a decision can be made within 2-3 weeks of receipt of an application although under some circumstances this may take a little longer. Tissue can be sent to  applicants once all  approvals have been obtained and tissue is prepared. This can take several weeks depending on the size and complexity of the tissue request.  A Material Transfer Agreement will be drawn up between Newcastle University and the recipient's institution. Local researchers will be asked to  sign a Local User Agreement.
If you have any questions or to obtain an application form, please contact the NBTR Manager, Debbie Lett
(  ) 





Looking for tissue for your study?
We may have what you are looking for! NBTR welcomes applications from researchers, both academic and commercial. Samples are available from donors with neurodegenerative disease , such as Alzheimer's Disease, Lewy Body Disease, Parkinsons Disease, Motor Neuron disease and Frontotemporal dementia as well as other rare kinds of dementia, mitochondrial disease and cognitively and neurologically normal controls. Tissue is preserved in a variety of ways to enable maximum research use. Let us know if you would like to discuss whether we have what you need!